Cellectis Nom. buy spalato
Summary
This prediction ended on 14.09.15 with a price of €29.00. The price of Cellectis Nom. has decreased during the runtime of the prediction. Compared to the start price this resulted in a performance of -16.55%. spalato has 50% into this predictionPerformance without dividends (%)
| Name | 1w | 1m | 1y | 3y |
|---|---|---|---|---|
| Cellectis Nom. | -2.037% | -2.037% | 31.349% | -84.798% |
| iShares Core DAX® | 0.961% | -2.210% | 12.839% | 17.154% |
| iShares Nasdaq 100 | 2.626% | -1.918% | 38.498% | 45.463% |
| iShares Nikkei 225® | 0.217% | -7.216% | 19.425% | 5.076% |
| iShares S&P 500 | 1.540% | -1.858% | 27.801% | 42.583% |
Comments by spalato for this prediction
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ellectis is an international pharmaceutical company headquartered in Paris, France. It is focused on developing and offering immunotherapies based on gene-edited CAR-T cells (UCART). Unlike other companies in the CAR-T space, Cellectis offers allogeneic CAR-T cells, which allows it to produce an off-the-shelf alternative. The company plans to utilize its validated genome-editing technology to delete the T-cell receptor (TCR) from CAR-T cells. By deleting the TCR, the CAR-T cells are no longer able to detect "non-self", thus theoretically allowing T-cells from unrelated donors to be transplanted into recipients without the risk of graft-versus-host disease. This allogeneic cell production can be standardized and controlled, while autologous cells cannot, because they are sampled from individual patients. The company has a Phase I clinical trial using anti-CD19 CAR-T cells to treat ALL and CLL planned to start in Q2 2015.
Cellectis has two major big pharma partners - Servier Laboratories and Pfizer (NYSE:PFE), which provide clinical and regulatory expertise. Under the Pfizer collaboration announced in June 2014, Cellectis received $80M, funding for Pfizer-selected CAR-T targets, and up to $185M in milestones from eachcandidate Pfizer develops (~12 targets), and then finally, tiered royalties on any future sales. The cash and support from the Servier/Pfizer partnerships serve to buffer both financial and development risks moving forward. Cellectis currently has a market cap of $803.74M, $20.21M in cash, and a quarterly burn of $2M.