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PRME Revenue Misses by 73%


Prime Medicine (NASDAQ:PRME), a genetic medicine innovator developing next-generation gene editing therapies, released its second quarter 2025 earnings on August 7, 2025. The company reported GAAP revenue of $1.1 million, substantially below analyst estimates of $4.18 million and driven solely by collaboration revenue. Earnings per share (GAAP) came in at $(0.41). While the company reduced its net loss (GAAP) compared to Q2 2024, it continues to report persistent operating losses. This quarter stood out for major clinical progress in Prime Editing technology, a sharper pipeline focus, and a significant extension of cash reserves to fund operations into 2027. However, the shortfall in revenue (GAAP) and ongoing loss reflect continued challenges for pre-commercial genetic medicine companies.

Source: Analyst estimates provided by FactSet. Management expectations based on management's guidance, as provided in Q3 2025 earnings report.

Prime Medicine is working to advance a new class of gene editing therapies. Its technology, Prime Editing, is designed to precisely repair disease-causing genetic mutations in human DNA without causing double-strand breaks. This approach enables more accurate and versatile correction, insertion, or deletion of DNA, potentially treating a wide range of genetic disorders. The company leverages partnerships and internal research to push its therapies through the clinic.

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Source Fool.com

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