Here's Why AC Immune Jumped Higher Today
Shares of AC Immune (NASDAQ: ACIU) are up 26% at 2:23 p.m. EDT after the biotech revealed top-line results from an early-stage clinical trial testing its Alzheimer's disease vaccine, ACI-35.030, which AC Immune is developing with Johnson & Johnson (NYSE: JNJ). Based on the results, the companies plan to test a higher dose of the vaccine in the phase 1b/2a study.
The press release was light on the details, only disclosing that AC Immune and Johnson & Johnson had seen "encouraging interim safety, tolerability and immunogenicity results from the initial dosing group."
Safety and tolerability are what you'd expect to see at the lowest level of a dose-escalation study like the companies are running. "Immunogenicity" likely refers to the ability of ACI-35.030 to spur the development of antibodies against phospho-Tau, a protein implicated in the development of Alzheimer's disease. There was no disclosure on whether the vaccine was able to improve cognition, which is what patients and their caregivers ultimately care about.
Source Fool.com
