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13th International Symposium on Bioorganic Chemistry (ISBOC-13)
IUPAC | International Union of Pure and Applied Chemistry
The symposium aims at further enhancing the communication among the chemical biology research fields such as bio-organic chemistry, medicine and...
4 months ago
Two-photon nanoprobes based on bioorganic nanoarchitectonics with a photo-oxidation enhanced emission mechanism
Nature
Two-photon absorption (TPA) fluorescence imaging holds great promise in diagnostics and biomedicine owing to its unparalleled spatiotemporal...
8 months ago
Cerevance Announces Publication of CVN766 in Bioorganic & Medicinal Chemistry Letters
GlobeNewswire
CVN766 is a potent antagonist of the orexin 1 receptor with high selectivity over the orexin 2 receptor which may benefit a variety of...
2 months ago
Formation of osteoconductive biograft with bioorganic scaffold, human mesenchymal stromal cells, and platelet rich ...
ScienceDirect.com
In bioengineering of bone tissue, biomaterials that are combining the properties of porosity (microstructure), bioactivity (osteoinductivity,...
1 month ago
What is Bioorganic Chemistry?
News-Medical
It is used to determine the interactions, reactivity, and structure of organic compounds of biological significance. This is different from...
29 months ago
Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement
ScienceDirect.com
The virally encoded 3C-like protease (3CLpro) is a well-validated drug target for the inhibition of coronaviruses including Severe Acute...
2 months ago
Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity ...
ScienceDirect.com
Diverse drug design strategies viz. molecular hybridization, substituent installation, scaffold hopping, isosteric replacement, high-throughput screening,...
7 months ago
mRNA incorporation of C(5)-halogenated pyrimidine ribonucleotides and induced high expression of corresponding ...
ScienceDirect.com
C(5)-halogenated pyrimidine ribonucleotides were synthesized. •. Synthesized C(5)-halogenated ribonucleotides show successful incorporation into the mRNA.
7 months ago
Targeting the epigenetic reader “BET” as a therapeutic strategy for cancer
ScienceDirect.com
Bromodomain and extraterminal (BET) proteins have the ability to bind to acetylated lysine residues present in both histones and non-histone proteins.
7 months ago
Unlocking InhA: Novel approaches to inhibit Mycobacterium tuberculosis
ScienceDirect.com
Multidrug-resistant tuberculosis continues to pose a health security risk and remains a public health emergency.
2 months ago